Effects of cholecystokinin-octapeptide and cerulein on small-intestinal motility in sheep

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Effects of cholecystokinin-octapeptide and cerulein on small-intestinal motility in sheep

Cholecystokinin (CCK) affects the intestinal motility but in ruminants the question has not been entirely explored. The aim of this study was to examine the precise effects of CCK-octapeptide (CCK-OP) and its amphibian analogue, cerulein, on duodenal motor activity in unfasted rams in the course of chronic experiments. Five rams underwent the implantation of a strain gauge force transducer to t...

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Cholecystokinin Octapeptide and Cerulein Inhibit Ovine Duodenal Motility in a Dose- and Region-specific Manner

The aim of this study was to examine the influence of cholecystokinin (CCK)-octapeptide (OP) and its amphibian analogue cerulein infusions on duodenal myoelectric and motor activities, as well as to compare the effects of CCK peptides on duodenal bulb and duodenal motility in non-fasted conscious rams. Five rams underwent implantation of bipolar platinum electrodes to the duodenal bulb, and dis...

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Dose-related effects of cerulein short infusions on proximal small bowel motility in sheep.

The effect of cholecystokinin (CCK) upon the intestinal motility has not been entirely explored in ruminants. The aim of this study was to examine the precise effects of CCK amphibian analogue, cerulein, on small-intestinal myoelectric activity in rams in the course of chronic experiments. Five rams underwent implantation of bipolar platinum electrodes to the duodenal bulb, the distal duodenum ...

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Regional effects of cholecystokinin octapeptide on colonic phasic and tonic motility in healthy humans.

The aim of this study was to assess in nine healthy subjects the effects of CCK octapeptide (CCK-8) on colonic tonic activity, measured by a barostat, and phasic activity, measured by manometry. On 2 consecutive days, recordings were performed in the unprepared proximal and distal colons during intravenous infusion of saline and CCK-8 at 5, 20, and 40 ng ⋅ kg-1 ⋅ h-1. In the proximal colon CCK-...

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ژورنال

عنوان ژورنال: Czech Journal of Animal Science

سال: 2010

ISSN: 1212-1819,1805-9309

DOI: 10.17221/1692-cjas